Brandy Brook Avenue was originally the easternmost tenth of a mile of River Street, after its junction with Lake Flower Avenue. The name was created as part of Saranac Lake's implementation of the 911 Emergency Response System. It is named for Brandy Brook, which the street parallels as it drains Moody Pond into Lake Flower.
| Old Address | Post-911 Address | Building Name/Notes | Cure Evidence | |
| Starts at the end of River Street (the Lake Flower Avenue continues east | ||||
| 138 River Street | 3 Brandy Brook Avenue |
 |
River Street School | |
| 145 River Street |
|
145 River Street (now Gauthier's Motel) | DIS | |
| 148 River Street | 15 Brandy Brook Avenue |
|
Pendragon Theatre | |
| 147 River Street |
|
Kingston Cottage | DIS 1911 | |
| 150 River Street | 25 Brandy Brook Avenue |
 |
150 River Street, Original Moody homestead, General Ice Cream | |
| 151 River Street | Brandy Brook Avenue |
 |
Captain Thomas Cottage (torn down), Cure Cottages, p. 105 | |
| 154 River Street |
|
See 150 River Street | ||
| 155 River Street | 34 Brandy Brook Avenue |
|
155 River Street | |
| 157 River Street | 38 Brandy Brook Avenue |
|
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| 159 River Street | 42 Brandy Brook Avenue |
|
159 River Street | USC1910 |
| 175 River Street | 167 River Street |
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| Ends at Pine Street | ||||
